Vulnerability · Published Sep 8, 2025 · Assigned by GitHub_M

CVE-2025-58757MONAI's unsafe use of Pickle deserialization may lead to RCE

High 8.8

In plain English

A high-severity unsafe deserialization in MONAI from Project-MONAI. Proof-of-concept exploit code is public. The chance it is exploited in the next 30 days is estimated at 0.6% (higher than 51% of all known vulnerabilities). Fixed versions are available - upgrade the affected package.

Severity (CVSS 3.1)8.8High

Exploit odds (30 days)0.6%top 48.9% of all CVEs

Exploited in the wildNo reportsCISA SSVC: poc

Attack toolingNoneno public tooling known

Official description

MONAI (Medical Open Network for AI) is an AI toolkit for health care imaging. In versions up to and including 1.5.0, the `pickle_operations` function in `monai/data/utils.py` automatically handles dictionary key-value pairs ending with a specific suffix and deserializes them using `pickle.loads()` . This function also lacks any security measures. The deserialization may lead to code execution. As of time of publication, no known fixed versions are available.

Affected packages & fixed versions

Ecosystem	Package	Fixed in	Advisory
PyPI	monai	1.5.1	GHSA-p8cm-mm2v-gwjm
PyPI	monai	1.5.1rc1	PYSEC-2025-142

Affected products (as reported)

Vendor	Product	Versions
Project-MONAI	MONAI	<= 1.5.0

Weakness: CWE-502 · Vector: CVSS:3.1/AV:N/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H

References

https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-p8cm-mm2v-gwjm x_refsource_CONFIRM