Vulnerability · Published Sep 27, 2026 · Assigned by VulnCheck

CVE-2026-100846MONAI before 1.5.2 Remote Code Execution via Pickle Deserialization

High 7.6

In plain English

A high-severity unsafe deserialization in MONAI from Project-MONAI. Proof-of-concept exploit code is public. The chance it is exploited in the next 30 days is estimated at 0.4% (higher than 30% of all known vulnerabilities). Fixed versions are available - upgrade the affected package.

Severity (CVSS 3.1)7.6High

Exploit odds (30 days)0.4%top 69.9% of all CVEs

Exploited in the wildNo reportsCISA SSVC: poc

Attack toolingNoneno public tooling known

Official description

MONAI before 1.5.2 contains a deserialization of untrusted data vulnerability in the algo_from_pickle function in monai/auto3dseg/utils.py. The function reads a .pkl file and passes its contents to pickle.loads without validating the data source or content. If an application invokes algo_from_pickle on an attacker-supplied pickle file, an object defining __reduce__ is executed during deserialization, resulting in arbitrary code execution in the context of the application.

Affected packages & fixed versions

Ecosystem	Package	Fixed in	Advisory
PyPI	monai	1.6.0	GHSA-89gg-p5r5-q6r4
PyPI	monai	1.5.2	PYSEC-2026-4021

Affected products (as reported)

Vendor	Product	Versions
Project-MONAI	MONAI	0 – before 1.5.2

Weakness: CWE-502 · Vector: CVSS:3.1/AV:N/AC:H/PR:H/UI:R/S:C/C:H/I:H/A:H

References

GitHub Security Advisory (GHSA-89gg-p5r5-q6r4) vendor-advisory
VulnCheck Advisory: MONAI before 1.5.2 Remote Code Execution via Pickle Deserialization third-party-advisory