Vulnerability · Published Nov 9, 2025 · Assigned by VulDB
CVE-2025-12921OpenClinica Community Edition CRF Data Import ImportCRFData xml injection
Medium 4.3
In plain English
A medium-severity injection in Community Edition from OpenClinica. Proof-of-concept exploit code is public. The chance it is exploited in the next 30 days is estimated at 0.6% (higher than 48% of all known vulnerabilities).
Official description
A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.
Affected products (as reported)
| Vendor | Product | Versions |
|---|---|---|
| OpenClinica | Community Edition | 3.03.13.23.33.43.53.63.7 |
Weakness: CWE-91, CWE-74 · Vector: CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N/E:P/RL:X/RC:R
References
- VDB-331641 | OpenClinica Community Edition CRF Data Import ImportCRFData xml injection vdb-entry, technical-description
- VDB-331641 | CTI Indicators (IOB, IOC, TTP, IOA) signature, permissions-required
- Submit #680872 | OpenClinica OpenClinica Community Edition 3.13, Changeset 74f4df3481b6 (2017-02-28) and 3.12.2, Changeset 347dcfca3d17 (2016-11-21) XML Injection third-party-advisory
- https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md related
- https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc exploit